Skip to main content
Skip to main menu Skip to spotlight region Skip to secondary region Skip to UGA region Skip to Tertiary region Skip to Quaternary region Skip to unit footer

Slideshow

Analytical Approaches for Measuring the Safety of Biotherapeutic Drugs

Biotherapeutic drugs present new analytical challenges to the drug development and quality control process. Unlike traditional small molecule drugs where synthetic choices can be tightly controlled, biotherapeutic drugs rely on the integrity of host cell biosynthetic machinery to manufacture the drug. The host cells themselves also present an issue where the biotherapeutic product can be contaminated with trace amounts of host cell proteins (HCPs).

Type of Event:

Dynamic Isotopic Detection of Aminosugars With Glutamine (IDAWG) for Released Glycans and O-GlcNAc Modified Proteins

The Isotopic Detection of Aminosugars With Glutamine (IDAWG) method was originally developed for the glycomics field as a quantitative tool that takes advantage of the hexosamine biosynthetic pathway, isotopically labeling nitrogen-containing glycans in cell culture systems via the use of 15N-Gln1,2.

Type of Event:

Analysis of Microbial Volatile Organic Compounds Using Solid Phase Microextraction Gas Chromatography Mass Spectrometry

Microbial volatile organic compounds (MVOCs) like ketones, alcohols, terpenes, and terpene derivatives are primary and secondary metabolites of fungi and bacteria1 . Indoor environments with varying amounts of humidity, lack of light, oxygen, and carbon dioxide create the breeding ground for MVOCs. Prolonged human exposure to MVOCs has been directly associated with sick building syndrome (SBS), respiratory irritation, and asthma-like symptoms1 .

Type of Event:

X-ray absorption spectroscopy and its application: X-ray fluorescene imaging

Dramatic advances in the understanding of X-ray absorption fine structure (XAFS) have been made over the past few decades, which have led ultimately to a highly quantitative theory. X-ray absorption fine structure (XAFS) refers to the oscillatory structure in the x-ray absorption coefficient just above an x-ray absorption edge. This turns out to be a unique signature of a given material; it also depends on the detailed atomic structure and electronic and vibrational properties of the material.

Type of Event:

The use of heterogeneous and melt miscible nucleating agents for the improvement of the crystallization rate of Poly(hydroxybutyrate-co-hydroxyhexanoate)

Since the 1950s, plastic production has steadily increased with millions of metric tons accumulating in the environment.1 Much of the waste stream is single use plastics, and the need for biodegradable alternatives is pressing. Polyhydroxyalkanoates (PHA), a class of polymers produced by many bacteria as a carbon source, presents a viable biodegradable replacement for many commodity thermoplastics such as polypropylene and polyethylene.

Type of Event:

Support Us

We appreciate your financial support. Your gift is important to us and helps support critical opportunities for students and faculty alike, including lectures, travel support, and any number of educational events that augment the classroom experience. Click here to learn more about giving.

Every dollar given has a direct impact upon our students and faculty.

Got More Questions?

Undergraduate inquiries: chemreg@uga.edu 

Registration and credit transferschemreg@uga.edu

AP Credit, Section Changes, Overrides, Prerequisiteschemreg@uga.edu

Graduate inquiries: chemgrad@uga.edu

Contact Us!

Assistant to the Department Head: Donna Spotts, 706-542-1919 

Main office phone: 706-542-1919 

Main Email: chem-web@franklin.uga.edu

Head of Chemistry: Prof. Jason Locklin