Tags: Organic Seminar


Asymmetric Deoxygenative Functionalization of Carboxylic Acids and Alcohols

Given that carboxylic acid derivatives and alcohols are abundant in a wide range of building blocks and complex molecules, catalytic diversification of these functional groups is highly sought-after.  To this end, recently employing a deoxygenative approach for modifying these oxygenated species has gained momentum.  However, to date, asymmetric variants of these methods have been underdeveloped and often require precious metal…


New Electron-Transfer Concepts in Organic Synthesis

The Nacsa Group uses electron transfer techniques to address challenges in organic synthesis. Our lab works in two main areas. The first uses electrochemistry to develop new approaches for dehydration reactions, such as the synthesis of amides and esters from carboxylic acids, with an emphasis on catalysis. Dehydrative transformations are workhorse operations in pharmaceutical R&D, but owing to the wasteful reagents overwhelmingly used to…


Literature Seminar: Zachary Dorward


Literature Seminar: Angel Yang


Research Seminar: Christopher DeAngelis


Research Seminar: Weihao Ma


Development and Applications of Ring-Closing Alkyne Metathesis (RCAM) in Natural Product Synthesis

Ring-closing alkyne metathesis (RCAM) has received considerable attention over the last 20 years for its utility in synthesizing macrocycles[1]. While its more widely studied counterpart—alkene metathesis—has become a cornerstone of modern synthetic methodology for macrocycle formation, alkyne metathesis remains comparatively unexplored[2]. However, recent studies have highlighted the synthetic potential of cycloalkynes as versatile…


Guest Speaker: Prof. Andy Thomas


Guest Speaker: Prof. Daniel Weix


Literature Seminar: Shivani Nagode

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