The faculty engaged in Organic Chemistry research have interdisciplinary programs that span the field of chemistry, including bioorganic mechanisms, complex carbohydrates, molecular recognition, biotechnology, natural products structure elucidation, new materials, organometallic synthesis, polymers, supramolecular assembly, synthetic methodology, total synthesis, and theoretical investigations of molecular structure.  Our program offers the chance to obtain graduate education in chemistry in a department with state-of-the-art facilities and an active faculty.

Personnel

Our research interest focuses on the synthesis and biological functions of carbohydrates and glycoconjugates. Before the 1970s, scientists solely considered carbohydrates as energy sources, structural components, and protective agents. However, it is now well established that in the living cell carbohydrates play key roles in many crucial…

Organic Chemistry

Research in our group is focused on the development of new synthetic transformations, primarily centered around transition metal catalysis.  Critical to the invention of these methods is our ability to derive inspiration from both reaction mechanisms and natural products.  Our understanding of intermediates along…

The research programs in our laboratory are centered on the investigation and development of novel materials and methods for the precise control of organic molecular assemblies, both in solution and on surfaces as ultrathin films.  Our research activities involve organic and polymer synthesis, surface sensitive characterization techniques, nano…

We are currently engaged in the development of organic methodologies toward the synthesis of active pharmaceutical ingredients. Our recently patented methodology for the decarboxylation of natural and synthetic amino acids utilizes microwave promotion to yield bioactive amines. This work is supported by Innovation Gateway at UGA and the Georgia…

Enzymes are remarkable biocatalysts, not only for the dramatic rate accelerations (up to 1020 fold) that they provide, but also for the high degree of substrate specificity, regiospecificity and stereospecificity that these reactions exhibit. The work in my laboratory is focused on the chemical basis for how enzymes achieve such high rates and…

Photoswitchable bioactive compounds: Photoactivation of drugs, enzymes, and other bio-molecules allows for achieving of the spatial and temporal control of their action. We design and synthesize compounds that are inactive in the dark but are converted into bioactive form upon irradiation with light of an appropriate wavelength. One of our…

The Wheeler Group works to understand the effects that govern noncovalent interactions through the application of computational chemistry and to exploit these interactions in the design of more effective asymmetric catalysts, organic materials, and pharmaceuticals. A hallmark of their work is the emphasis on building predictive conceptual…