Given that carboxylic acid derivatives and alcohols are abundant in a wide range of building blocks and complex molecules, catalytic diversification of these functional groups is highly sought-after.  To this end, recently employing a deoxygenative approach for modifying these oxygenated species has gained momentum.  However, to date, asymmetric variants of these methods have been underdeveloped and often require precious metal catalysts.  This presentation will include our efforts addressing these challenges.  The Kim Group at C

N-linked glycosylation is an important post translational modification, and the changes in N-glycan patterns are known to be associated with various human diseases. The study of N-glycans is crucial for the safety and efficacy of biotherapeutics. Tandem mass spectrometry (MS/MS) is a popular method in glycomics where glycans are identified via their mass to charge (m/z) and fragment ions. However, glycans exist as isomers arising from linkage, anomeric, and stereochemical differences.