DAD: A Novel Reaction or an Old Dog with New Tricks Carbon-carbon bond cleavage remains a frequently difficult synthetic task, yet nature is built upon the making and breaking of carbon-carbon bonds through enzyme-catalyzed reactions. One example, 2,4’-dihydroxyacetophenone dioxygenase (DAD), catalyzes the oxidative cleavage of the α-hydroxyketone side-chain of 2,4’-dihydroxyacetophenone (DHAP). While this enzyme has only been cursorily investigated, the DAD reaction bears notable similarity to the cleavage performed by the better understood, acireductone dioxygenase (ARD’). Type of Event: Organic Seminar Read more about DAD: A Novel Reaction or an Old Dog with New Tricks
CO Releasing Complexes Using Two Photon Excitation for Therapy Throughout history carbon monoxide (CO) has been thought of as a toxic gas.1 However, over the past 60 years CO was found to be endogenous with distinct physiological functions and a large therapeutic potential.2, 3 4 As a therapeutic, CO modulates the immune system, exerts redox control in the mitochondria, acts as a cytoprotective, and is a vasodilator. Type of Event: Inorganic Seminar Read more about CO Releasing Complexes Using Two Photon Excitation for Therapy
Who We Are, What We Do, and Why We Do It Type of Event: Inorganic Seminar Read more about Who We Are, What We Do, and Why We Do It
