Apisata Holt^1,2, Yajan Yan^1,2,3, and Jason Locklin^1,2,3

¹Department of Chemistry, University of Georgia, Athens, Georgia, 30602, United States,

²New Materials Institute, University of Georgia, Athens, Georgia, 30602, United States,

³College of Engineering, University of Georgia, Athens, Georgia, 30602, United States

Photodynamic therapy (PDT) is a relatively new cancer treatment modality where light is used to activate photosensitizer molecules to produce toxic radicals.¹ Recently, PDT is found to induce anticancer immunity while killing cancer cells. However, the immunity is often not strong enough to prevent systemic tumor control or tumor recurrence.²

Chromatography, despite being a technique over a century old, is a staple in modern chemical analysis. Its applications have become so broad since its inception due to developments in instrumentation, such as high-performance liquid chromatography and gas chromatography, and equally so due to the chemistries and structures of the stationary phases.

Oxidation of hydrocarbons is comprised of a series of chemical reactions that are in constant competition based on the conditions of the reaction environment. Further understanding of these pathways and the implications of this competition is important to improving the efficiency of combustion systems used for transportation. To calculate the contribution of each reaction, quantification of the intermediates formed must be conducted. However, these intermediates either have a short lifespan or are formed from various complex reaction networks.

Singlet Fission (SF) is a process, in which a singlet excited state is converted into two triplet excited states within a molecular system ^[1] . From an application point of view, SF in the molecular semiconductor is known to generate triplet excitons that are energetically matched to the bandgap of silicon or perovskite ^[2] .

The synthesis of highly strained molecules has garnered significant interest from the chemical community over the last few decades. The tetrahedral isomer of the C₄H₄ molecule (tetrahedrane) is a prototypical example of a strained molecule and remains elusive to experimental chemists despite its predicted theoretical kinetic stability[1]. Earlier this year Cummins and coworkers published a groundbreaking study in which they successfully isolated the PC₃(t-Butyl)₃ derivative of tetrahedrane[2].

Controlled placement of molecules is a necessary step for the future of nanoscale synthetic methods. Although layer deposition methods provide a bottom-up process for the construction of microscopic structures, the lack of precision limits the minimum size of these designs.

Since its discovery in the late 1940s, hydrosilylation reactions have become crucial in both industrial and laboratory settings to form silicon-carbon and silicon-oxygen bonds.^1,2 Since Speier's exploration into chloroplatinic acid catalyzed olefin hydrosilylation, precious metal catalysts have been widely implemented for the production of silicon products including adhesives and rubber.² It is estimated that the silicon industry worldwide consumes around 5,600 kilograms of platinum each year.³ Given the cost, toxicity, and low a