Significant scientific attention has been spent on the elucidation of protein’s structure to explain its function. Lots of proteins stay around cell membrane or vesicles to facilitate cellular metabolism. These proteins usually form monolayer structure around cell membrane/vesicles and therefore cause challenges for the measurements of X-ray crystallography and NMR, which cannot provide high resolution results for proteins in monolayer.

Glycation is an important post-translational modification that is linked to diabetes, cataract, Alzheimer’s, Rheumatoid arthritis and Parkinson’s disease.¹ This reaction occurs between a reducing sugar and a primary amine at the N-terminus of protein or the sidechain of Lysine residues.  Ultimately this interaction leads to advanced glycation end products (AGEs) that are associated with several disease complications.² Glycation could also occur during the manufacturing and storage of therapeutic proteins,

Exposure to microplastics and nanoplastics throughout daily life is inevitable, yet still poses a variety of unknowns and concerns in biological and environmental systems. Microplastics are defined by the National Oceanic and Atmospheric Association (NOAA) as all plastic particles <5mm in size; either produced to be that size (primary) or via degradation of larger particles (secondary). Ubiquitous in nature, microplastics have successfully infiltrated marine systems, foodstuffs, soil/sediments, and biological systems.

Secondary organic aerosol (SOA) is formed in the atmosphere through the oxidation of volatile organic compounds (VOCs) and represents a significant portion of global submicron-sized atmospheric organic aerosol. SOA plays a crucial role in multiple processes that impact climate and human health.

Nuclear power has broad application prospects as a kind of clean energy. One of the biggest controversies in the development of nuclear energy has been the potential environmental impact of spent fuel (SNF), which is the raw material of incomplete reactions and toxic byproducts.  At present, people still use landfills to deal with SNF residues, whether for low-level radioactive wastes or high-radioactive wastes after separation and transmutation.  Effective monitoring methods will greatly reduce the environmental hazards of these landfil

The herquline family of natural products were originally isolated from penicillium herquei in 1979 by the Ōmura group (see figure below). These strained macrocyclic alkaloids all contain multiple stereocenters, and an unsymmetrically substituted piperazine. Herqulines B and C feature two β,γ-unsaturated cyclohexenones, while herquline A bears an additional pyrrolidine.

The use of metal–hydrogen atom transfer (MHAT) for olefin hydrofunctionalization has received great attention over the last 20 years, primarily due to its enhanced chemoselectivity and regioselectivity.^[1] The Giese reaction, or the addition of a carbon-centered radical into an electron-deficient alkene, is well-known and has been commonly employed for C–C bond formation over the last 40 years.^[2] More recently, the Baran group coupled these two methodologies to establish a powerful tool for the reductive cross-coupling of

Oceans produce one of the largest global natural sources of aerosol in the form of sea spray aerosol (SSA) particles which therefore play a large role in global climate dynamics. SSA particles are enriched in ocean-derived organic compounds, specifically surfactants, which influence the chemical properties of SSA and the potential for SSA particles to become cloud seeds.