Tags: Departmental Colloquium

How non-covalent interactions contribute to gas-phase bond energies. What is the design behind Vitamin B12? Homolytic dissociation of the weak Co-C bond in Vitamin B12 (adenosylcobalamine), an essential cofactor in a large number of enzymes, initiates radical reactions.  Modulation of the bond dissociation energy is accordingly a key element in control of enzymatic activity, although one would ordinarily consider homolytic bond…
Comprehensive redesign and implementation of an organic chemistry curriculum is a complex and multi-faceted undertaking. All revisions must sustain academic rigor and support continuing modifications. Unfortunately, external metrics designed to measure the success of comprehensive curriculum changes are uncommon or only marginally helpful. Our unique metrics developed in conjunction with curriculum redesign will be discussed. In addition to…
Stacking interactions, which are roughly parallel face-to-face interactions between planar π-systems, play important roles in chemical and biochemical systems. Our ability to predict and rationally tune the strength of these interactions is important in everything from the design of new organic materials and catalysts to structure-based drug design. I will discuss our decade-long effort to develop quantitative and qualitative models of stacking…
Nanophotonics involves the development of fundamental science, materials, and applications that leverage the interaction of light and matter on the nanometer to micrometer length scales. This growing and highly interdisciplinary field involves chemistry, materials science, physics, engineering, and bio-science. In this presentation Dr. Kuebler will introduce the field of nanophotonics and describe some work done by his group in this area. The…
Nanoscale polymeric particles, in particular self-assembled block copolymer micelles, have been utilized in pharmaceutics for development of novel therapeutic and diagnostic modalities. Advantages of the polymeric micelles include their small size, long circulation in bloodstream, ability to circumvent renal excretion and extravasation at sites of enhanced vascular permeability. They can be designed to facilitate the incorporation of a variety…
  Acknowledging the limitations of traditional curricula and pedagogy, this seminar will describe the process of designing a new four-year curriculum at Emory University. The major goals of this reform effort include an emphasis on core ideas and scientific practices rather than content and historical course boundaries in order to convey the excitement, relevance, and interdisciplinary nature of 21st century chemistry to undergraduate…
The Computational and Theoretical Chemistry Group (CATCO) at Southern Methodist University (SMU) is devoted to the development and coding of quantum chemical methods and their application to pending chemical problems. A potpourri of research topics will be presented including: i) The elucidation of chemical bonding and weak chemical interactions with the Local Vibrational Mode Theory ranging from catalyst and materials design to structural…