Tags: Inorganic Seminar


Unraveling Heme Metabolism in Malaria Parasites

Malaria remains a devastating infectious disease, with symptoms caused by Plasmodium parasite invasion of erythrocytes. During blood-stage infection, parasites import and digest up to 80% of host cell hemoglobin. This massive catabolic process liberates vast amounts of heme, which parasites detoxify by sequestering it into crystalline hemozoin within an acidic digestive vacuole. Eukaryotic Plasmodium parasites also require heme as a metabolic…
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