Tags: Analytical Seminar


Obtaining Ambient Organic Aerosol Volatility Using the Filter Inlet for Gas and Aerosol Phase (FIGAERO)

Aerosols are a suspension of solid or liquid particles in a gas. They can influence the climate directly through scattering or absorption of solar radiation, or indirectly through their ability to act as cloud condensation nuclei. Tropospheric aerosols are comprised from an organic as well as inorganic phase with the organic phase being a major constituent. Organic aerosol composition is affected by both chemical and physical atmospheric…


Ambient Ionization Mass Spectrometry Application in Therapeutic Drug Monitoring

Therapeutic drug monitoring (TDM) is a quantitative test that measures drug dosage to prevent underdose or overdose in clinical practice [1]. Ultrahigh sensitivity and selectivity techniques such as mass spectrometry has superior advantages over traditional immunoassay technique in the diagnosis and quantification of therapeutic drug [2]. While liquid chromatography coupled with mass spectrometry has shown to be a "golden standard" for TDM [1,2…


Identification of Glycosaminoglycans with MS-Based Analytical Techniques

Glycosaminoglycans (GAGs) are linear anionic polysaccharides that play many important biological functions such as cell-signaling, cell recognition, inflammation, angiogenesis on the cell surface1. However, the structural heterogeneity of GAGs and their low abundance in biological systems have made their analysis difficult2. There has been much interest over the decades to characterize the structures of GAGs to better understand their function…


The Evolution of C=C Position Elucidation in Lipid Fatty Acyl Chains

Determining the unique isomeric structures of lipids is vital to understanding their biochemical functions in organisms. Distinct lipid isomers have been directly linked to a variety of disease states and properties of cellular membranes. Being able to distinguish between C=C positional isomers has proven to be particularly difficult. Traditional methods of C=C position elucidation included complex derivatization of the…


Reverse Metabolomics: An Answer for Characterizing the Functional Relationship of Bile Acids and the Gut

Bile acids (BA) are synthesized in the liver from cholesterol and utilized by the body through primary taurine and glycine (de)conjugation, while secondary BA salts undergo de-hydroxylation, dehydration, and epimerization of the cholesterol backbone. They have been linked to several well understood and unknown disease states in systems biology. Structural characterization of bile acid derivatives continues to be a challenge in metabolomic…


The Analytical Chemistry of Sports Doping Control

Performance enhancing drug (PED) use is a historic issue at the highest levels of professional competition, driving use in young amateurs and compromising the healthfulness of sport. Legal criteria for detecting PED use in athlete’s urine and blood have been in continuous development for 40 years. Illicit use of endogenous substances such as testosterone cannot be established by their presence in fluids. High precision isotope ratio mass…


Evaluating Extraction Techniques for Quantifying Residual Antibiotics Found in Honey using Triple Quadrupole Mass Spectrometry

Honey is a widely sought-after natural product produced around the globe. It’s produced by honeybees that take up nectar from flowers and digest it in a separate stomach full of enzymes necessary to break down nectar sugar. The partially digested nectar is passed from honeybee to honeybee until its placed inside a honeycomb and dried via flapping wings. The honey is then sealed off with beeswax. Extracting honey from beehives has had the same…


Exploiting Chemical Modifications for Structural Elucidation by Mass Spectrometry

Chemical modifications combined with mass spectrometry have been extensively used for identification and quantification of compounds of interest. Applications range from sample derivatization to the use of bioconjugation and chemical probes of protein structure. The Webb Lab uses solution and gaseous chemistries to facilitate the identification of compounds and their three-dimensional structures. We have used derivatization in the gas phase, a…


New Frontiers in Photodissociation Mass Spectrometry: Challenges and Solutions

Advances in mass spectrometry instrumentation and experimental design have led to significant inroads in the characterization of biological molecules like proteins and lipids, thus translating to new applications in the field of proteomics, lipidomics and structural biology. Ultraviolet photodissociation (UVPD) is a fast, higher energy ion activation mode that results in extensive and information fragmentation of molecules, and ion activation/…


Graphene Oxide Quantum Dots as a Sensing Platform for the Detection of Pathogenic Bacteria

Graphene oxide quantum dots (GQDs) are a zero-dimensional (0D) nanomaterial of the carbon family that has attracted much attention in biomedical applications. Top-down and bottom-up approaches are used to synthesize GQDs. Exfoliation of carbon precursors from GQDs is a top-down strategy that includes chemical exfoliation, electrochemical exfoliation, hydrothermal/solvothermal exfoliation, and microwave/ultrasound-assisted exfoliation, whereas…
Subscribe to Analytical Seminar

Support Us

We appreciate your financial support. Your gift is important to us and helps support critical opportunities for students and faculty alike, including lectures, travel support, and any number of educational events that augment the classroom experience. Click here to learn more about giving.

Every dollar given has a direct impact upon our students and faculty.

Got More Questions?

Undergraduate inquiries: chemreg@uga.edu 

Registration and credit transfers: chemreg@uga.edu

AP Credit, Section Changes, Overrides, Prerequisites: chemreg@uga.edu

Graduate inquiries: chemgrad@uga.edu

Contact Us!

Assistant to the Department Head: Donna Spotts, 706-542-1919 

Main office phone: 706-542-1919 

Main Email: chem-web@franklin.uga.edu

Head of Chemistry: Prof. Jason Locklin