Tags: Organic Seminar


Improvement of Poly-3-hydroxybutyrate-co-3-hydroxyhexanoate Nucleation for Use in Waterborne and Biologically Degradable Polymer Coating

Single-use plastics plague our oceans as landfills overflow and waste is mismanaged. Jambeck et al estimated that only 30% of all plastic ever produced are currently in use, and in 2015 only 9% was recycled.[1] The packaging and single-use plastics industry are two main contributors to this ever increasing amount of plastic production and pollution. To reduce waste accumulated in landfills the single-use abuse of environmentally persisting…


Cis/trans Photoisomerization: From Photoswitches to Light-Activated Molecular Rotary Motors

Over the past few decades synthetic chemists were striving to make a leap from simple molecular switches to molecular systems with controlled dynamic behavior. These research efforts were inspired by directional motion in living systems that are key to almost every essential process in the cell. The structure of molecular rotary motors resembles the layout of macroscopic electric motors which are widely used to convert energy into motion.…


TBA - Timothy Henkel


Applying X-Ray crystallography for elucidating enantioselective alcohol dehydrogenase/carbonyl reductase enzyme – substrate interactions

The use of microorganisms in fermentation for ethanol production or in bio-catalysis for drug synthesis has been attracting attention of scientist over the past few decades because it efficient, cost-effective, and environment-friendly. The aim of my research project is applying X-Ray crystallography to investigate the enzyme structures of enantioselective Alcohol dehydrogenase (ADH) and Carbonyl reductase (CAR) from these organisms to elucidate…


TBA - Jeff Costello


Proteomimetic Foldamers for Biomolecular Recognition


(Towards) The Rapid Generation of Structural Complexity


Controlling Chemical Reactivity: From Small Molecules to Polymers


Mechanistic Insights Facilitate the Development of Transition Metal Catalyzed Processes


New Strategies in Radical-Based Aliphatic C-H Fluorination

  In 2018, almost 50% of all small-molecule drugs approved by the FDA contained fluorine. The appeal of fluorine substitution in drug candidates can be attributed to the improved properties fluorine exerts on a molecule such as blocking undesired metabolism and increasing potency, absorption, or binding affinities. Incorporation of the radio isotope, [18F], to bioactive molecules also has applications in medical imaging as well as…
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