Tags: Analytical Seminar

 Native mass spectrometry is an emerging approach for characterizing the stoichiometry, assembly, and shapes of protein complexes in solution. Native mass spectrometry is especially useful for investigating proteins and protein complexes that are challenging to characterize using condensed-phase experiments, including those that are heterogeneous, have large mass, and are membrane bound. I will discuss how my lab uses mass spectrometry, ion…
In the past, cellular imaging, and biological analyte assays utilize traditional fluorescence-based techniques. However, since most conventional fluorescence-based probes display only modest fluorescent changes, low sensitivity, low specificity, and so on, those methods have been limited by those drawbacks.1 Recently developed FRET-based probes can overcome those limitations largely to detect and monitor molecular targets in live cells in vitro…