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Slideshow

Tags: Materials Chemistry and Nanoscience Seminar

In 2021, Americans spent $525 million on oral solid dosage forms, of which tablets made up 53.1% of the market. (1). Tablets are the most popular drug delivery method because of the relatively low cost of ingredients, ease of manufacturing, and high patient compliance (1). In the early stages of formulation development, when drug availability is limited and expensive (2), the current methodology of making  tablet formulations require…
Block copolymer membranes offer a bottom-up approach to form isoporous membranes that are useful for ultrafiltration of functional macromolecules, colloids, and water purifcation. Experimentally, the fabrication of isoporous block copolymer membranes from a mixed film of an asymmetric block copolymer and two solvents involves two stages: First, the volatile solvent evaporates, creating a dense polymer skin, in which the block copolymer self-…
The continual rise of plastic production globally has placed a heightened focus on the end of life destination for this durable products.1 Replacing current nondegradable commodity plastics with degradable alternatives, specifically those that are compostable, can help alleviate the disposal burden that these products present.2 Through the application of a high-throughput fluorescence based enzymatic degradation screening method, we have…
Egyptian blue is considered the first synthetic pigment, dating back to the 3rd millennium BC1. It is a layered calcium copper silicate material with the chemical composition CaCuSi4O10. Later, a related family of these layered silicates were discovered— Han blue (BaCuSi4O10), and Han Purple (BaCuSi2O6)2. The layered silicates EB, HB, and HP are known as historic pigments, but they also possess novel optoelectronic properties with strong…
With globalization and the spreading availability of technologies, nuclear proliferation challenges continue to grow and evolve. Savannah River National Laboratory (SRNL) works to counter proliferation by providing scientific and technological solutions, as well as expert advice to combat emerging threats. Working with the National Nuclear Security Administration (NNSA) and other government agencies, SRNL’s Global Security Directorate provides…
The treatment of ischemic stroke remains a daunting task as few therapeutic strategies have proven to be effective. Systemic thrombolysis with intravenous tissue plasminogen activator (tPA) remains the only proven treatment to improve clinical outcome of patients with acute ischemic stroke. But because of an increased risk of hemorrhage beyond 4.5 hours after onset of stroke, only certain stroke patients (1-2%) can benefit from tPA treatment.…
The project is based on the hypothesis that SCNPs can break the osmotic balance across the plasma membrane of cancer cells. Ion homeostasis is essential for maintaining the integrity of the plasm membrane and sustaining the normal cell functions. Breaking the homeostasis could disrupt the potential balance and interrupt essential cellular processes. Instead of using organic ionophores, we explore SCNPs as a new strategy to carry ions across the…
With the ever rising production of plastic globally, a renewed focus has been cast onto the end of life fate of these persisting products.1 Within this sphere, chemical recycling to monomers is a high interest area that focuses on the application of depolymerization to return plastics into reusable monomers in order to produce a truly circular plastic recycling economy.2 Within this field, the two main focuses are on either finding novel…

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