Current Research

The research programs in our laboratory are centered on the investigation and development of novel materials and methods for the precise control of organic molecular assemblies, both in solution and on surfaces as ultrathin films.  Our research activities involve organic and polymer synthesis, surface sensitive characterization techniques, nano- and micropatterning, and materials and device characterization. The approach we take is multidisciplinary, which involves chemistry, physics, bioengineering, and materials science. The devices of interest currently are enzymatic biofuel cells, smart polymer actuators, hybrid organic photovoltaic cells, and chemical and biological sensors. These devices are used as tools to investigate fundamental interfacial phenomena and to obtain a better understanding of inter- and intramolecular interactions that govern thin film architecture.  They are also of practical interest for nano- and microscale electronics, low cost and large area flexible plastic circuits, displays and disposable sensors.

Selected Publications

Brooks, K. ; Yatvin, J. ; McNitt, C. D. ; Reese, R. A. ; Jung, C. ; Popik, V. V. ; Locklin, J. Multifunctional Surface Manipulation Using Orthogonal Click Chemistry. Langmuir 2016, 32, 6600-6605.
Roy, A. ; Bougher, T. L. ; Geng, R. ; Ke, Y. ; Locklin, J. ; Cola, B. A. Thermal Conductance of Poly(3-methylthiophene) Brushes. ACS Appl Mater Interfaces 2016, 8, 25578-25585.
Yatvin, J. ; Brooks, K. ; Locklin, J. SuFEx Click: New Materials from SOx F and Silyl Ethers. Chemistry European Journal 2016.
Grubbs, J. B. ; Arnold, R. M. ; Roy, A. ; Brooks, K. ; Bilbrey, J. A. ; Gao, J. ; Locklin, J. Degradable Polycaprolactone and Polylactide Homopolymer and Block Copolymer Brushes Prepared by Surface-Initiated Polymerization with Triazabicyclodecene and Zirconium Catalysts. Langmuir 2015, 31, 10183-10189.
Yatvin, J. ; Brooks, K. ; Locklin, J. SuFEx on the Surface: A Flexible Platform for Postpolymerization Modification of Polymer Brushes. Angew Chem Int Ed 2015, 54, 13370-13373.
Zhu, T. ; Cheng, R. ; Sheppard, G. R. ; Locklin, J. ; Mao, L. Magnetic-Field-Assisted Fabrication and Manipulation of Nonspherical Polymer Particles in Ferrofluid-Based Droplet Microfluidics. Langmuir 2015, 31, 8531-8534.
Brooks, K. ; Razavi, M. J. ; Wang, X. ; Locklin, J. Nanoscale Surface Creasing Induced by Post-polymerization Modification. ACS Nano 2015, 9, 10961-10969.
Fries, K. H. ; Sheppard, G. R. ; Bilbrey, J. A. ; Locklin, J. Tuning chelating groups and comonomers in spiropyran-containing copolymer thin films for color-specific metal ion binding. Polymer Chemistry 2014, 5, 2094.
Sontag, K. S. ; Bilbrey, J. A. ; Huddleston, E. N. ; Sheppard, G. R. ; Allen, W. D. ; Locklin, J. π-Complexation in Nickel-Catalyzed Cross-Coupling Reactions. The Journal of Organic Chemistry 2014, 79, 1836 - 1841.
Arumugam, S. ; Orski, S. V. ; Mbua, N. Eric; McNitt, C. ; Boons, G. - J. ; Locklin, J. ; Popik, V. V. Photo-click chemistry strategies for spatiotemporal control of metal-free ligation, labeling, and surface derivatization. Pure and Applied Chemistry 2013, 85.
Bilbrey, J. A. ; Kazez, A. H. ; Locklin, J. ; Allen, W. D. Exact ligand cone angles. Journal of Computational Chemistry 2013, 34, 1189 - 1197.
Zhou, J. ; Samanta, S. ; Guo, C. ; Locklin, J. ; Xu, B. Measurements of contact specific low-bias negative differential resistance of single metalorganic molecular junctions. Nanoscale 2013, 5, 5715.
White, E. M. ; Yatvin, J. ; Grubbs, J. B. ; Bilbrey, J. A. ; Locklin, J. Advances in smart materials: Stimuli-responsive hydrogel thin films. Journal of Polymer Science Part B: Polymer Physics 2013, 51, 1084 - 1099.
White, E. M. ; Seppala, J. E. ; Rushworth, P. M. ; Ritchie, B. W. ; Sharma, S. ; Locklin, J. Switching the Adhesive State of Catecholic Hydrogels using Phototitration. Macromolecules 2013, 46, 8882 - 8887.
Bilbrey, J. A. ; Sontag, K. S. ; Huddleston, E. N. ; Allen, W. D. ; Locklin, J. On the Role of Disproportionation Energy in Kumada Catalyst-Transfer Polycondensation. ACS Macro Letters 2012, 995 - 1000.
Arumugam, S. ; Orski, S. V. ; Locklin, J. ; Popik, V. V. Photoreactive Polymer Brushes for High-Density Patterned Surface Derivatization Using a Diels–Alder Photoclick Reaction. Journal of the American Chemical Society 2012, 134, 179 - 182.
Arnold, R. M. ; Huddleston, E. N. ; Locklin, J. Utilizing click chemistry to design functional interfaces through post-polymerization modification. Journal of Materials Chemistry 2012.
Dhende, V. P. ; Samanta, S. ; Jones, D. M. ; Hardin, I. R. ; Locklin, J. One-Step Photochemical Synthesis of Permanent, Nonleaching, Ultrathin Antimicrobial Coatings for Textiles and Plastics. ACS Applied Materials & Interfaces 2011, 3, 2830 - 2837.
Fries, K. H. ; Driskell, J. D. ; Sheppard, G. R. ; Locklin, J. Fabrication of Spiropyran-Containing Thin Film Sensors Used for the Simultaneous Identification of Multiple Metal Ions. Langmuir 2011, 27, 12253 - 12260.
Sontag, K. S. ; Sheppard, G. R. ; Usselman, N. M. ; Marshall, N. ; Locklin, J. Surface-Confined Nickel Mediated Cross-Coupling Reactions: Characterization of Initiator Environment in Kumada Catalyst-Transfer Polycondensation. Langmuir 2011, 27, 12033 - 12041.
Orski, S. V. ; Fries, K. H. ; Sontag, K. S. ; Locklin, J. Fabrication of nanostructures using polymer brushes. Journal of Materials Chemistry 2011, 21, 14135.
Hensarling, R. M. ; Rahane, S. B. ; LeBlanc, A. P. ; Sparks, B. J. ; White, E. M. ; Locklin, J. ; Patton, D. L. Thiol–isocyanate “click” reactions: rapid development of functional polymeric surfaces. Polymer Chemistry 2011, 2, 88.
Marshall, N. ; Sontag, K. S. ; Locklin, J. Surface-initiated polymerization of conjugated polymers. Chemical Communications 2011, 47, 5681.
Sheppard, G. ; Oseki, T. ; Baba, A. ; Patton, D. ; Kaneko, F. ; Mao, L. ; Locklin, J. Thiolene-based microfluidic flow cells for surface plasmon resonance imaging. Biomicrofluidics 2011, 5, 026501.
Orski, S. V. ; Fries, K. H. ; Sheppard, G. R. ; Locklin, J. High Density Scaffolding of Functional Polymer Brushes: Surface Initiated Atom Transfer Radical Polymerization of Active Esters. Langmuir 2010, 26, 2136-2143.
Marshall, N. ; Sontag, S. K. ; Locklin, J. Substituted Poly(p-phenylene) Thin Films via Surface-Initiated Kumada-Type Catalyst Transfer Polycondensation. Macromolecules 2010, 43, 2137-2144.
Fries, K. H. ; Driskell, J. D. ; Samanta, S. ; Locklin, J. Spectroscopic Analysis of Metal Ion Binding in Spiropyran Containing Copolymer Thin Films. Analytical Chemistry 2010, 82, 3306-3314.
Orski, S. V. ; Poloukhtine, A. A. ; Arumugam, S. ; Mao, L. ; Popik, V. V. ; Locklin, J. High Density Orthogonal Surface Immobilization via Photoactivated Copper-Free Click Chemistry. Journal of the American Chemical Society 2010, 132, 11024-11026.
Sontag, S. K. ; Marshall, N. ; Locklin, J. Formation of conjugated polymer brushes by surface-initiated catalyst-transfer polycondensation. Chemical Communications 2009, 3354-3356.
Fries, K. ; Samanta, S. ; Orski, S. ; Locklin, J. Reversible colorimetric ion sensors based on surface initiated polymerization of photochromic polymers. Chemical Communications 2008, 6288-6290.